In Brief: The (molecular) pathogenesis of Barrett's oesophagus. Issue 4 (March 2014)

• Record Type: Journal Article
• Authors: Aichler, Michaela; Walch, Axel
• Is Part Of: Journal of pathology. Volume 232:Issue 4(2014)
• Page Start: 383
• Page End: 385
• Publication Date: 2014-03
• Subjects: Pathology -- Periodicals; 616.07
• DOI: 10.1002/path.4300
• Languages: English
• ISSNs: 0022-3417

Abstract

<abstract abstract-type="main" id="path4300-abs-0001"> <title>Abstract</title> <p id="path4300-para-0001"> <bold>Barrett's oesophagus is a metaplastic change, such that the normal squamous epithelial lining of the oesophagus is replaced by specialized columnar‐lined epithelium. Barrett's oesophagus is clinically significant and has a high health economic impact as it is associated with heightened risk of progression to oesophageal adenocarcinoma. This review discusses the pathogenesis of Barrett's oesophagus with an emphasis on the underlying molecular events. Copyright © 2013 Pathological Society of Great Britain and Ireland. Published by John Wiley &amp; Sons, Ltd.</bold> </p> </abstract>