Hyperphagia: Current concepts and future directions proceedings of the 2nd international conference on hyperphagia. (February 2014)

• Record Type: Journal Article
• Authors: Heymsfield, Steven B.; Avena, Nicole M.; Baier, Leslie; Brantley, Phillip; Bray, George A.; Burnett, Lisa C.; Butler, Merlin G.; Driscoll, Daniel J.; Egli, Dieter; Elmquist, Joel; Forster, Janice L.; Goldstone, Anthony P.; Gourash, Linda M.; Greenway, Frank L.; Han, Joan C.; Kane, James G.; Leibel, Rudolph L.; Loos, Ruth J.F.; Scheimann, Ann O.; Roth, Christian L.; Seeley, Randy J.; Sheffield, Val; Tauber, Maïthé; Vaisse, Christian; Wang, Liheng; Waterland, Robert A.; Wevrick, Rachel; Yanovski, Jack A.; Zinn, Andrew R.
• Is Part Of: Obesity. Volume 22:Number 1(2014:Jan.)
• Page Start: S1
• Page End: S17
• Publication Date: 2014-02
• Subjects: Obesity -- Periodicals; 616.398005
• DOI: 10.1002/oby.20646
• Languages: English
• ISSNs: 1930-7381

Abstract

<abstract abstract-type="main"> <title> <x xml:space="preserve">Abstract</x> </title> <sec id="oby20646-sec-0001" sec-type="section"> <title>Objective</title> <p>Hyperphagia is a central feature of inherited disorders (e.g., Prader–Willi Syndrome) in which obesity is a primary phenotypic component. Hyperphagia may also contribute to obesity as observed in the general population, thus raising the potential importance of common underlying mechanisms and treatments. Substantial gaps in understanding the molecular basis of inherited hyperphagia syndromes are present as are a lack of mechanistic of mechanistic targets that can serve as a basis for pharmacologic and behavioral treatments.</p> </sec> <sec id="oby20646-sec-0002" sec-type="section"> <title>Design and Methods</title> <p>International conference with 28 experts, including scientists and caregivers, providing presentations, panel discussions, and debates.</p> </sec> <sec id="oby20646-sec-0003" sec-type="section"> <title>Results</title> <p>The reviewed collective research and clinical experience provides a critical body of new and novel information on hyperphagia at levels ranging from molecular to population. Gaps in understanding and tools needed for additional research were identified.</p> </sec> <sec id="oby20646-sec-0004" sec-type="section"> <title>Conclusions</title> <p>This report documents the full scope of important topics reviewed at a comprehensive international meeting devoted to the topic of hyperphagia and identifies key areas for future funding and research.</p> </sec> </abstract>