Heat‐Induced Dry Tailoring of Porosity in Polymer Scaffolds. Issue 11 (17th December 2012)

• Record Type: Journal Article
• Authors: Hild, Nora; Abaecherli, Matteo L.; Mohn, Dirk; Stark, Wendelin J.
• Is Part Of: Macromolecular materials and engineering. Volume 298:Issue 11(2013:Nov.)
• Page Start: 1143
• Page End: 1148
• Publication Date: 2012-12-17
• Subjects: Plastics -- Periodicals; Polymers -- Periodicals; Polymerization -- Periodicals; 547.705
• DOI: 10.1002/mame.201200327
• Languages: English
• ISSNs: 1438-7492

Abstract

<abstract abstract-type="main" xml:lang="en"> <title>Abstract</title> <p>The present study evaluates the effect of heat treatment on electrospun poly(lactide‐<italic>co</italic>‐glycolide) fibrous membranes. Both a temperature (75–150 °C) and a treatment time range (5–40 min) are tested. The effect on the fibrous structure is investigated in terms of morphology, showing that with increasing temperature or longer treatment time the fusion of fibres progresses continuously. Additionally, the tensile properties of the various scaffolds deliver results on the effect of increasing fibre‐to‐fibre linkages. Both modulus and yield increase within the heat treatment procedures. The elevated stiffness of the membranes accompanies a loss in porosity. These findings deliver insights into the tailoring of membranes that might be used in the fabrication of customised scaffolds intended for cell culture in tissue engineering. <boxed-text content-type="graphic" position="anchor" orientation="portrait"><graphic position="anchor" mimetype="image" xlink:href="ark:/27927/pgg4t88zhz3" orientation="portrait" xlink:type="simple" xmlns:xlink="http://www.w3.org/1999/xlink" /></boxed-text></p> </abstract>