Drug‐induced sleep endoscopy in sleep‐disordered breathing: Report on 1, 249 cases. (11th December 2013)

• Record Type: Journal Article
• Authors: Vroegop, Anneclaire V.; Vanderveken, Olivier M.; Boudewyns, An N.; Scholman, Joost; Saldien, Vera; Wouters, Kristien; Braem, Marc J.; Van de Heyning, Paul H.; Hamans, Evert
• Is Part Of: Laryngoscope. Volume 124:Number 3(2014:Mar.)
• Page Start: 797
• Page End: 802
• Publication Date: 2013-12-11
• Subjects: Otolaryngology -- Periodicals; 617.51005
• DOI: 10.1002/lary.24479
• Languages: English
• ISSNs: 0023-852X

Abstract

<abstract abstract-type="main"> <title> <x xml:space="preserve">Abstract</x> </title> <sec id="lary24479-sec-0001" sec-type="section"> <title>Objectives/Hypothesis</title> <p>To describe upper airway (UA) collapse patterns during drug‐induced sleep endoscopy (DISE) in a large cohort of patients with sleep‐disordered breathing (SDB) and to assess associations with anthropometric and polysomnographic parameters.</p> </sec> <sec id="lary24479-sec-0002" sec-type="section"> <title>Study Design</title> <p>Observational study.</p> </sec> <sec id="lary24479-sec-0003" sec-type="section"> <title>Methods</title> <p>A total of 1, 249 patients [age 47 ± 10 y; apnea–hypopnea index (AHI) 18.9 ± 15.3/h; body mass index (BMI) 27.2 ± 3.7 kg/m<sup>2</sup>] underwent polysomnography and DISE. DISE findings were categorized to the following UA levels: palate, oropharynx, tongue base, and hypopharynx. The degree of collapse was reported as complete, partial, or none. The pattern of the obstruction was described as anteroposterior, lateral, or concentric. Associations between DISE findings and anthropometric and polysomnographic parameters were analyzed.</p> </sec> <sec id="lary24479-sec-0004" sec-type="section"> <title>Results</title> <p>Palatal collapse was seen most frequently (81%). Multilevel collapse was noted in 68.2% of all patients. The most frequently observed multilevel collapse pattern was a combination of palatal and tongue base collapse (25.5%). Palatal collapse was seen most frequently (81%). The prevalence of complete collapse, multilevel collapse, and hypopharyngeal collapse increased with increasing severity of obstructive sleep apnea (OSA). Multilevel and complete collapse were more prevalent in obese patients and in those with more severe OSA. Both higher BMI and AHI values were associated with a higher probability of complete concentric palatal collapse.</p> </sec> <sec id="lary24479-sec-0005" sec-type="section"> <title>Conclusion</title> <p>The current study provides an overview of UA collapse patterns in a large cohort of SDB patients who underwent DISE. The associations found in this study may indicate that UA collapse patterns observed during DISE cannot be fully explained by selected baseline polysomnographic and anthropometric characteristics.</p> </sec> <sec id="lary24479-sec-0006" sec-type="section"> <title>Level of Evidence</title> <p>4. <italic>Laryngoscope</italic>, 124:797–802, 2014</p> </sec> </abstract>