Appropriate gastrectomy resection margins for early gastric carcinoma. Issue 3 (19th November 2013)

• Record Type: Journal Article
• Authors: Kim, Beom Su; Oh, Seong Tae; Yook, Jeong Hwan; Kim, Hee Sung; Lee, In Seob; Kim, Byung Sik
• Is Part Of: Journal of surgical oncology. Volume 109:Issue 3(2014:Mar. 01)
• Page Start: 198
• Page End: 201
• Publication Date: 2013-11-19
• Subjects: Cancer -- Surgery -- Periodicals; Neoplasms -- Periodicals; 616
• DOI: 10.1002/jso.23483
• Languages: English
• ISSNs: 0022-4790

Abstract

<abstract abstract-type="main"> <title> <x xml:space="preserve">Abstract</x> </title> <sec id="jso23483-sec-0001" sec-type="section"> <title>Objective</title> <p>In Korea and Japan, early gastric cancer (EGC) accounts for >50% of all gastric cancers. Here, we propose recommendations for the optimal distance from the tumor to the resection margins when evaluating EGC.</p> </sec> <sec id="jso23483-sec-0002" sec-type="section"> <title>Summary of Background Data</title> <p>There are very few guidelines regarding the distance from the EGC tumor to the resection margins.</p> </sec> <sec id="jso23483-sec-0003" sec-type="section"> <title>Methods</title> <p>We evaluated 2, 081 patients who underwent gastrectomy for EGC between January 1989 and May 2000. We subdivided tumors according to the distance from the proximal margin: ≤1, >1, ≤10, >10, ≤30, or >30 mm.</p> </sec> <sec id="jso23483-sec-0004" sec-type="section"> <title>Results</title> <p>Three of five patients demonstrating distances ≤1 mm between the tumor and gross proximal margin were microscopically positive. No patients with gross proximal margins >1, ≤10, >10, or ≤30 mm were microscopically positive. There were no statistical differences in rates of microscopically positive margin, reresection, or reoperation between groups (<italic>P</italic> > 0.05). In addition, there were statistical differences in terms of tumor recurrence and disease‐related death between groups (<italic>P</italic> > 0.05).</p> </sec> <sec id="jso23483-sec-0005" sec-type="section"> <title>Conclusions</title> <p>When the resection margins are clear, we propose that margins >1 mm are adequate for EGC gastrectomy. <italic>J. Surg. Oncol. 2014 109:198–201</italic>. © 2013 Wiley Periodicals, Inc.</p> </sec> </abstract>