Validity of bioelectrical impedance analysis to assess fat‐free mass in patients with head and neck cancer: An exploratory study. Issue 4 (17th January 2014)

• Record Type: Journal Article
• Authors: Jager–Wittenaar, Harriët; Dijkstra, Pieter U.; Earthman, Carrie P.; Krijnen, Wim P.; Langendijk, Johannes A.; van der, Bernard F.A.M.; Pruim, Jan; Roodenburg, Jan L.N.
• Is Part Of: Head & neck. Volume 36:Issue 4(2014:Apr.)
• Page Start: 585
• Page End: 591
• Publication Date: 2014-01-17
• Subjects: Head -- Diseases -- Periodicals; Neck -- Diseases -- Periodicals; Head -- Periodicals; Neck -- Periodicals; Face -- Periodicals; 617.51059
• DOI: 10.1002/hed.23336
• Languages: English
• ISSNs: 1043-3074

Abstract

<abstract abstract-type="main"> <title> <x xml:space="preserve">Abstract</x> </title> <sec id="hed23336-sec-0001" sec-type="section"> <title>ABSTRACT: Background</title> <p>The purpose of this study was to validate bioelectrical impedance analysis (BIA) using the Geneva equation for fat‐free mass (FFM) in patients with head and neck cancer.</p> </sec> <sec id="hed23336-sec-0002" sec-type="section"> <title>Methods</title> <p>In 24 patients with head and neck cancer, agreement between BIA (FFM<sub>BIA</sub>) and dual energy x‐ray absorptiometry (FFM<sub>DXA</sub>) 1 week before (T<sub>0</sub>), 1 month (T<sub>1</sub>), and 4 months (T<sub>2</sub>) after cancer treatment was analyzed.</p> </sec> <sec id="hed23336-sec-0003" sec-type="section"> <title>Results</title> <p>FFM<sub>BIA</sub> did not differ from FFM<sub>DXA</sub> (mean difference 0.71 ± 1.9, 0.30 ± 1.9, and 0.02 ± 2.1 kg) at any time point. Only at T<sub>0</sub>, mean FFM correlated to the difference between FFM<sub>DXA</sub> and FFM<sub>BIA</sub> (<italic>r</italic> = 0.48; <italic>p</italic> = .017). Limits of agreement were 3.8, 3.7, and 4.1 kg, respectively. Concordance Correlation Coefficients were 0.98 at all time points.</p> </sec> <sec id="hed23336-sec-0004" sec-type="section"> <title>Conclusion</title> <p>BIA may be used to assess FFM with reasonable validity based on mean‐level comparisons, but differences between BIA and DXA may vary by about 4 kg in an individual patient. These results require confirmation in a larger sample of patients with head and neck cancer. © 2013 Wiley Periodicals, Inc. <italic>Head Neck</italic><bold>36</bold>: 585–591, 2014</p> </sec> </abstract>