Dialkylation of Diethyl Ethoxycarbonylmethylphosphonate under Microwave and Solventless Conditions. Issue 2 (4th March 2014)

• Record Type: Journal Article
• Authors: Grün, Alajos; Blastik, Zsófia; Drahos, László; Keglevich, György
• Is Part Of: Heteroatom chemistry. Volume 25:Issue 2(2014:Mar.)
• Page Start: 107
• Page End: 113
• Publication Date: 2014-03-04
• Subjects: Heterocyclic chemistry -- Periodicals; 547.59
• DOI: 10.1002/hc.21142
• Languages: English
• ISSNs: 1042-7163

Abstract

<abstract abstract-type="main"> <title>ABSTRACT</title> <p>To further broaden the methods for the heterogeneous phase alkylation of CH acidic compounds, the dialkylation of diethyl ethoxycarbonylmethylphosphonate was studied in the presence of Cs₂CO₃ under microwave and solvent‐free conditions. It was found that after repeating the alkylations by the addition of newer portions of the alkylating agent and the base on a few occasions, the dialkylation was quite efficient. Even dialkyl derivatives with different alkyl groups could be synthesized. The presence of a phase‐transfer catalyst was harmful, as prevented the formation of the dialkyl products.</p> </abstract>