Mec1 and Tel1: an arresting dance of resection. (22nd January 2014)

• Record Type: Journal Article
• Authors: Beyer, Tracey; Weinert, Ted
• Is Part Of: EMBO journal. Volume 33:Number 3(2014)
• Page Start: 176
• Page End: 178
• Publication Date: 2014-01-22
• Subjects: Molecular biology -- Periodicals; 572.805
• DOI: 10.1002/embj.201387440
• Languages: English
• ISSNs: 0261-4189

Abstract

<abstract abstract-type="main" id="embj201387440-abs-0001"> <title> <x xml:space="preserve">Abstract</x> </title> <p content-type="executiveSummary">At sites of damage DNA is resected to enable the optimal form of repair, directed by homology. But how does the cell regulate resection while coordinating with the cell cycle? In this issue of <italic>The EMBO Journal</italic>, Clerici <italic>et al</italic> define missing links between DNA resection and cell cycle arrest during repair, showing that Mec1 can inhibit resection to subsequently activate arrest by Tel1.</p> </abstract>