Direct α‐Alkylation of Ketones with Alcohols in Water. Issue 1 (20th November 2013)

• Record Type: Journal Article
• Authors: Xu, Guoqiang; Li, Qiong; Feng, Jiange; Liu, Qiang; Zhang, Zuojun; Wang, Xicheng; Zhang, Xiaoyun; Mu, Xindong
• Is Part Of: ChemSusChem. Volume 7:Issue 1(2014:Jan.)
• Page Start: 105
• Page End: 109
• Publication Date: 2013-11-20
• Subjects: Green chemistry -- Periodicals; Sustainable engineering -- Periodicals; Chemistry -- Periodicals; Chemical engineering -- Periodicals; 660
• DOI: 10.1002/cssc.201300815
• Languages: English
• ISSNs: 1864-5631

Abstract

<abstract abstract-type="main" xml:lang="en"> <title>Abstract</title> <p>The direct α‐alkylation of ketones with alcohols has emerged as a new green protocol to construct CC bonds with H₂O as the sole byproduct. In this work, a very simple and convenient Pd/C catalytic system for the direct α‐alkylation of ketones with primary alcohols in pure water is developed. Based on this catalytic system, aqueous mixtures of dilute acetone, 1‐butanol, and ethanol (mimicking ABE fermentation products) can be directly transformed into C₅–C₁₁ or longer‐chain ketones and alcohols, which are precursors to fuels.</p> </abstract>