Inside Cover: A Chemical Tool for In Vitro and In Vivo Precipitation of Lysine Methyltransferase G9a (ChemMedChem 3/2014). Issue 3 (March 2014) - Konze, Kyle D.
Abstract The inside cover picture shows chem‐ChIP, a method to examine occupancy of the lysine methyltranferase G9a on chromatin. UNC0965 (green) bridges streptavidin‐coupled magnetic beads (blue and yellow) and G9a (magenta). UNC0965 is cell permeable, which gives chem‐ChIP a distinct advantage over traditional in vitro antibody ChIP. For further details, see the Communication by Jian Jin et al. on p. 549 ff.