Back Cover: The Fatty Acid Composition of Diacylglycerols Determines Local Signaling Patterns (Angew. Chem. Int. Ed. 24/2013). Issue 24 (31st May 2013)

• Record Type: Journal Article
• Authors: Nadler, André; Reither, Gregor; Feng, Suihan; Stein, Frank; Reither, Sabine; Müller, Rainer; Schultz, Carsten
• Is Part Of: Angewandte Chemie international edition. Volume 52:Issue 24(2013)
• Page Start: 6340
• Page End: 6340
• Publication Date: 2013-05-31
• Subjects: Chemistry -- Periodicals; 540
• DOI: 10.1002/anie.201304203
• Languages: English
• ISSNs: 1433-7851

Abstract

<abstract abstract-type="graphical" xml:lang="en"> <title> <x xml:space="preserve">Abstract</x> </title> <p> <bold>Photoactivatable or "caged" derivatives</bold> of signaling molecules are important tools for manipulating intracellular events with spatial and temporal resolution. In their Communication on <ext-link ext-link-type="doi" xlink:type="simple" xmlns:xlink="http://www.w3.org/1999/xlink">page 6330 ff., </ext-link> C. Schultz and co‐workers demonstrate that regionally limited photoactivation simultaneously leads to a local protein kinase C and a global calcium response. Surprisingly, the orchestration of these effects seems to depend on the fatty acid composition of the released lipid.<boxed-text content-type="graphic" position="anchor" orientation="portrait"><graphic position="anchor" mimetype="image" xlink:href="ark:/27927/pgg21fg6hx8" orientation="portrait" xlink:type="simple" xmlns:xlink="http://www.w3.org/1999/xlink" /></boxed-text></p> </abstract>