Structure of the Parallel Duplex of Poly(A) RNA: Evaluation of a 50 Year‐Old Prediction1. Issue 39 (27th June 2013)

• Record Type: Journal Article
• Authors: Safaee, Nozhat; Noronha, Anne M.; Rodionov, Dmitry; Kozlov, Guennadi; Wilds, Christopher J.; Sheldrick, George M.; Gehring, Kalle
• Is Part Of: Angewandte Chemie international edition. Volume 52:Issue 39(2013)
• Page Start: 10370
• Page End: 10373
• Publication Date: 2013-06-27
• Subjects: Chemistry -- Periodicals; 540
• DOI: 10.1002/anie.201303461
• Languages: English
• ISSNs: 1433-7851

Abstract

<abstract abstract-type="graphical" xml:lang="en"> <title> <x xml:space="preserve">Abstract</x> </title> <p> <bold>The other double helix</bold>: The molecular structure of double‐stranded poly(rA) was predicted in 1961, but it has only now been confirmed. The crystal structure of the parallel double helix of (rA)₁₁ obtained at physiological pH was solved using ab initio direct methods and refined to 1.0 Å resolution. The crystals have bound ammonium ions that are complexed by the RNA phosphates and adenine N1 atoms (see section of the structure).<boxed-text content-type="graphic" position="anchor" orientation="portrait"><graphic position="anchor" mimetype="image" xlink:href="ark:/27927/pgg3h9k5f1r" orientation="portrait" xlink:type="simple" xmlns:xlink="http://www.w3.org/1999/xlink" /></boxed-text></p> </abstract>