Addressing Challenges in Palladium‐Catalyzed Cross‐Couplings of Aryl Mesylates: Monoarylation of Ketones and Primary Alkyl Amines1. Issue 28 (12th June 2013)

• Record Type: Journal Article
• Authors: Alsabeh, Pamela G.; Stradiotto, Mark
• Is Part Of: Angewandte Chemie international edition. Volume 52:Issue 28(2013)
• Page Start: 7242
• Page End: 7246
• Publication Date: 2013-06-12
• Subjects: Chemistry -- Periodicals; 540
• DOI: 10.1002/anie.201303305
• Languages: English
• ISSNs: 1433-7851

Abstract

<abstract abstract-type="graphical" xml:lang="en"> <title> <x xml:space="preserve">Abstract</x> </title> <p> <bold>Mor(DalPhos) for Me(sylates)</bold>: Described are the first examples of ketone mono‐α‐arylation and primary aliphatic amine monoarylation employing aryl methanesulfonate coupling partners. A range of functionalized aryl mesylates were employed with dialkyl ketones, and also with primary and secondary amines as well as the otherwise challenging coupling partners acetone and methylamine. Ad=adamantyl.<boxed-text content-type="graphic" position="anchor" orientation="portrait"><graphic position="anchor" mimetype="image" xlink:href="ark:/27927/pgg26mfwrvz" orientation="portrait" xlink:type="simple" xmlns:xlink="http://www.w3.org/1999/xlink" /></boxed-text></p> </abstract>