Back Cover: Catalytic Phenol Hydroxylation with Dioxygen: Extension of the Tyrosinase Mechanism beyond the Protein Matrix (Angew. Chem. Int. Ed. 20/2013). Issue 20 (22nd April 2013)

• Record Type: Journal Article
• Authors: Hoffmann, Alexander; Citek, Cooper; Binder, Stephan; Goos, Arne; Rübhausen, Michael; Troeppner, Oliver; Ivanović‐Burmazović, Ivana; Wasinger, Erik C.; Stack, T. Daniel P.; Herres‐Pawlis, Sonja
• Is Part Of: Angewandte Chemie international edition. Volume 52:Issue 20(2013)
• Page Start: 5408
• Page End: 5408
• Publication Date: 2013-04-22
• Subjects: Chemistry -- Periodicals; 540
• DOI: 10.1002/anie.201303052
• Languages: English
• ISSNs: 1433-7851

Abstract

<abstract abstract-type="graphical" xml:lang="en"> <title> <x xml:space="preserve">Abstract</x> </title> <p> <bold>Translating the catalytic mechanism</bold> of an enzyme to a synthetic complex is a challenging endeavor. In their Communication on <ext-link ext-link-type="doi" xlink:type="simple" xmlns:xlink="http://www.w3.org/1999/xlink">page 5398 ff., </ext-link> S. Herres‐Pawlis, T. D. P. Stack, and co‐workers present a complex capable of the efficient catalytic oxidation of phenols to quinones by using dioxygen. The mechanism of the synthetic system is similar to that of tyrosinase, yet the substrate scope extends beyond that of the enzyme. Thus this work fulfills a goal of bioinspired chemistry.<boxed-text content-type="graphic" position="anchor" orientation="portrait"><graphic position="anchor" mimetype="image" xlink:href="ark:/27927/pgg1zsxhxt1" orientation="portrait" xlink:type="simple" xmlns:xlink="http://www.w3.org/1999/xlink" /></boxed-text></p> </abstract>