Ruthenium–NHC‐Catalyzed Asymmetric Hydrogenation of Flavones and Chromones: General Access to Enantiomerically Enriched Flavanones, Flavanols, Chromanones, and Chromanols1. Issue 32 (1st July 2013)

• Record Type: Journal Article
• Authors: Zhao, Dongbing; Beiring, Bernhard; Glorius, Frank
• Is Part Of: Angewandte Chemie international edition. Volume 52:Issue 32(2013)
• Page Start: 8454
• Page End: 8458
• Publication Date: 2013-07-01
• Subjects: Chemistry -- Periodicals; 540
• DOI: 10.1002/anie.201302573
• Languages: English
• ISSNs: 1433-7851

Abstract

<abstract abstract-type="graphical" xml:lang="en"> <title> <x xml:space="preserve">Abstract</x> </title> <p> <bold>Two to four!</bold> Readily available flavones and chromones were efficiently converted into four valuable chiral classes of O‐heterocycles—flavanones, chromanones, flavanols, and chromanols—by means of an enantioselective Ru/NHC‐catalyzed hydrogenation process (see scheme; NHC=N‐heterocyclic carbene, PCC=pyridinium chlorochromate).<boxed-text content-type="graphic" position="anchor" orientation="portrait"><graphic position="anchor" mimetype="image" xlink:href="ark:/27927/pgg36jxcsv1" orientation="portrait" xlink:type="simple" xmlns:xlink="http://www.w3.org/1999/xlink" /></boxed-text></p> </abstract>