Multimodal Magnetic Core–Shell Nanoparticles for Effective Stem‐Cell Differentiation and Imaging1. Issue 24 (6th May 2013)

• Record Type: Journal Article
• Authors: Shah, Birju; Yin, Perry T.; Ghoshal, Shraboni; Lee, Ki‐Bum
• Is Part Of: Angewandte Chemie international edition. Volume 52:Issue 24(2013)
• Page Start: 6190
• Page End: 6195
• Publication Date: 2013-05-06
• Subjects: Chemistry -- Periodicals; 540
• DOI: 10.1002/anie.201302245
• Languages: English
• ISSNs: 1433-7851

Abstract

<abstract abstract-type="graphical" xml:lang="en"> <title> <x xml:space="preserve">Abstract</x> </title> <p> <bold>Special delivery!</bold> The title system, composed of a highly magnetic core surrounded by a thin uniform gold shell, has been synthesized and applied to the magnetically facilitated delivery of genetic material (siRNA or plasmid DNA) into neural stem cells (NSCs) for controlling their neural differentiation in a spatiotemporally controlled, biocompatible manner.<boxed-text content-type="graphic" position="anchor" orientation="portrait"><graphic position="anchor" mimetype="image" xlink:href="ark:/27927/pgg21fg69bs" orientation="portrait" xlink:type="simple" xmlns:xlink="http://www.w3.org/1999/xlink" /></boxed-text></p> </abstract>