Total Synthesis and Stereochemical Assignment of Baringolin1. Issue 30 (18th June 2013)

• Record Type: Journal Article
• Authors: Just‐Baringo, Xavier; Bruno, Paolo; Ottesen, Lars K.; Cañedo, Librada M.; Albericio, Fernando; Álvarez, Mercedes
• Is Part Of: Angewandte Chemie international edition. Volume 52:Issue 30(2013)
• Page Start: 7818
• Page End: 7821
• Publication Date: 2013-06-18
• Subjects: Chemistry -- Periodicals; 540
• DOI: 10.1002/anie.201302372
• Languages: English
• ISSNs: 1433-7851

Abstract

<abstract abstract-type="graphical" xml:lang="en"> <title> <x xml:space="preserve">Abstract</x> </title> <p> <bold>The thiopeptide antibiotic</bold> baringolin has been synthesized, and its structure and stereochemistry have been confirmed. The use of a strategy based on palladium‐catalyzed cross‐couplings permitted a modular construction of this natural product.<boxed-text content-type="graphic" position="anchor" orientation="portrait"><graphic position="anchor" mimetype="image" xlink:href="ark:/27927/pgg270w492p" orientation="portrait" xlink:type="simple" xmlns:xlink="http://www.w3.org/1999/xlink" /></boxed-text></p> </abstract>