Modifying Alkylzinc Reactivity with 2, 2′‐Dipyridylamide: Activation of tBuZn Bonds for para‐Alkylation of Benzophenone1. Issue 28 (5th June 2013)

• Record Type: Journal Article
• Authors: Armstrong, David R.; Garden, Jennifer A.; Kennedy, Alan R.; Mulvey, Robert E.; Robertson, Stuart D.
• Is Part Of: Angewandte Chemie international edition. Volume 52:Issue 28(2013)
• Page Start: 7190
• Page End: 7193
• Publication Date: 2013-06-05
• Subjects: Chemistry -- Periodicals; 540
• DOI: 10.1002/anie.201302426
• Languages: English
• ISSNs: 1433-7851

Abstract

<abstract abstract-type="graphical" xml:lang="en"> <title> <x xml:space="preserve">Abstract</x> </title> <p> <bold>Undercover agent</bold>: Masquerading as a simple donor‐acceptor complex (<bold>1</bold>), sodium amide substoichiometrically activates <italic>t</italic>Bu₂Zn for the challenging 1, 6‐addition of a <italic>tert‐</italic>butyl group to benzophenone. In contrast, the nonactivated <italic>t</italic>Bu₂Zn is ineffectual.<boxed-text content-type="graphic" position="anchor" orientation="portrait"><graphic position="anchor" mimetype="image" xlink:href="ark:/27927/pgg26mfvj6w" orientation="portrait" xlink:type="simple" xmlns:xlink="http://www.w3.org/1999/xlink" /></boxed-text></p> </abstract>