Hofmeister Salts Recover a Misfolded Multiprotein Complex for Subsequent Structural Measurements in the Gas Phase1. Issue 32 (1st July 2013)

• Record Type: Journal Article
• Authors: Han, Linjie; Ruotolo, Brandon T.
• Is Part Of: Angewandte Chemie international edition. Volume 52:Issue 32(2013)
• Page Start: 8329
• Page End: 8332
• Publication Date: 2013-07-01
• Subjects: Chemistry -- Periodicals; 540
• DOI: 10.1002/anie.201301893
• Languages: English
• ISSNs: 1433-7851

Abstract

<abstract abstract-type="graphical" xml:lang="en"> <title> <x xml:space="preserve">Abstract</x> </title> <p> <bold>A misfolded protein complex</bold> (see picture, red tetramer), which exists both in solution and in the gas phase, can be recovered back to a native‐like structure (blue) by the addition of salts prior to desorption/ionization into the gas phase using nano‐electrospray ionization.<boxed-text content-type="graphic" position="anchor" orientation="portrait"><graphic position="anchor" mimetype="image" xlink:href="ark:/27927/pgg36jxcb4q" orientation="portrait" xlink:type="simple" xmlns:xlink="http://www.w3.org/1999/xlink" /></boxed-text></p> </abstract>