A Bioorthogonal Raman Reporter Strategy for SERS Detection of Glycans on Live Cells1. Issue 28 (23rd May 2013)

• Record Type: Journal Article
• Authors: Lin, Liang; Tian, Xiangdong; Hong, Senlian; Dai, Peng; You, Qiancheng; Wang, Ruyi; Feng, Lianshun; Xie, Can; Tian, Zhong‐Qun; Chen, Xing
• Is Part Of: Angewandte Chemie international edition. Volume 52:Issue 28(2013)
• Page Start: 7266
• Page End: 7271
• Publication Date: 2013-05-23
• Subjects: Chemistry -- Periodicals; 540
• DOI: 10.1002/anie.201301387
• Languages: English
• ISSNs: 1433-7851

Abstract

<abstract abstract-type="graphical" xml:lang="en"> <title> <x xml:space="preserve">Abstract</x> </title> <p> <bold>Direct detection of glycans</bold> on live cells using surface‐enhanced Raman scattering (SERS) has been shown. A bioorthogonal Raman reporter was directly installed onto the monosaccharide analogs. Once metabolically incorporated into cell surface glycans, the Raman reporter was detected using SERS (see picture).<boxed-text content-type="graphic" position="anchor" orientation="portrait"><graphic position="anchor" mimetype="image" xlink:href="ark:/27927/pgg26mfvhvv" orientation="portrait" xlink:type="simple" xmlns:xlink="http://www.w3.org/1999/xlink" /></boxed-text></p> </abstract>