Inside Back Cover: Polymer Nanofiber‐Embedded Microchips for Detection, Isolation, and Molecular Analysis of Single Circulating Melanoma Cells (Angew. Chem. Int. Ed. 12/2013). Issue 12 (26th February 2013)

• Record Type: Journal Article
• Authors: Hou, Shuang; Zhao, Libo; Shen, Qinglin; Yu, Juehua; Ng, Charles; Kong, Xiangju; Wu, Dongxia; Song, Min; Shi, Xiaohong; Xu, Xiaochun; OuYang, Wei‐Han; He, Rongxian; Zhao, Xing‐Zhong; Lee, Tom; Brunicardi, F. Charles; Garcia, Mitch André; Ribas, Antoni; Lo, Roger S.; Tseng, Hsian‐Rong
• Is Part Of: Angewandte Chemie international edition. Volume 52:Issue 12(2013)
• Page Start: 3533
• Page End: 3533
• Publication Date: 2013-02-26
• Subjects: Chemistry -- Periodicals; 540
• DOI: 10.1002/anie.201301082
• Languages: English
• ISSNs: 1433-7851

Abstract

<abstract abstract-type="graphical" xml:lang="en"> <title> <x xml:space="preserve">Abstract</x> </title> <p>Transparent polymer‐nanofiber substrates combined with a laser microdissection technique, produced a new single‐cell isolation technology, as shown by M. A. Garcia, A. Ribas, R. S. Lo, H.‐R. Tseng, et al. in their Communication on <ext-link ext-link-type="doi" xlink:type="simple" xmlns:xlink="http://www.w3.org/1999/xlink">page 3379 ff.</ext-link> Using this new technique, single circulating melanoma cells (CMCs) were isolated from patients' blood for subsequent single‐cell genotyping to identify a mutation in a proto‐oncogene <italic>BRAF.</italic><boxed-text content-type="graphic" position="anchor" orientation="portrait"><graphic position="anchor" mimetype="image" xlink:href="ark:/27927/pgg1v78m5vc" orientation="portrait" xlink:type="simple" xmlns:xlink="http://www.w3.org/1999/xlink" /></boxed-text></p> </abstract>