Cover Picture: Palladium‐Catalyzed Oxidative Cross‐Coupling between Heterocycles and Terminal Alkynes with Low Catalyst Loading (Angew. Chem. Int. Ed. 13/2013). Issue 13 (21st February 2013)

• Record Type: Journal Article
• Authors: Jie, Xiaoming; Shang, Yaping; Hu, Peng; Su, Weiping
• Is Part Of: Angewandte Chemie international edition. Volume 52:Issue 13(2013)
• Page Start: 3535
• Page End: 3535
• Publication Date: 2013-02-21
• Subjects: Chemistry -- Periodicals; 540
• DOI: 10.1002/anie.201301067
• Languages: English
• ISSNs: 1433-7851

Abstract

<abstract abstract-type="graphical" xml:lang="en"> <title> <x xml:space="preserve">Abstract</x> </title> <p> <italic> <bold>The direct alkynylation</bold> </italic> of electron‐rich aromatic heterocycles with terminal alkynes was accomplished in high yields and good selectivity when using a low loading of palladium catalyst, as described by W. Su and co‐workers in their Communication on <ext-link ext-link-type="doi" xlink:type="simple" xmlns:xlink="http://www.w3.org/1999/xlink">page 3630 ff.</ext-link> A high loading of palladium catalyst led to poor yields because of the undesired homocoupling of alkynes.<boxed-text content-type="graphic" position="anchor" orientation="portrait"><graphic position="anchor" mimetype="image" xlink:href="ark:/27927/pgg1v8chzpt" orientation="portrait" xlink:type="simple" xmlns:xlink="http://www.w3.org/1999/xlink" /></boxed-text></p> </abstract>