Arene CHO Hydrogen Bonding: A Stereocontrolling Tool in Palladium‐Catalyzed Arylation and Vinylation of Ketones1. Issue 18 (3rd April 2013)

• Record Type: Journal Article
• Authors: Huang, Zhiyan; Lim, Li Hui; Chen, Zuliang; Li, Yongxin; Zhou, Feng; Su, Haibin; Zhou, Jianrong (Steve)
• Is Part Of: Angewandte Chemie international edition. Volume 52:Issue 18(2013)
• Page Start: 4906
• Page End: 4911
• Publication Date: 2013-04-03
• Subjects: Chemistry -- Periodicals; 540
• DOI: 10.1002/anie.201300621
• Languages: English
• ISSNs: 1433-7851

Abstract

<abstract abstract-type="graphical" xml:lang="en"> <title> <x xml:space="preserve">Abstract</x> </title> <p> <bold>Weak is powerful</bold>: For the arylation of tin enolates, the palladium catalyst engages in weak CHO hydrogen bonds to control stereoselectivity (see scheme). Similar catalysts capable of NHO hydrogen bonding also works well.<boxed-text content-type="graphic" position="anchor" orientation="portrait"><graphic position="anchor" mimetype="image" xlink:href="ark:/27927/pgg1xpsz551" orientation="portrait" xlink:type="simple" xmlns:xlink="http://www.w3.org/1999/xlink" /></boxed-text></p> </abstract>