Synthesis and Application of β‐Substituted Pauson–Khand Adducts: Trifluoromethyl as a Removable Steering Group1. Issue 20 (10th April 2013)

• Record Type: Journal Article
• Authors: Aiguabella, Nuria; del Pozo, Carlos; Verdaguer, Xavier; Fustero, Santos; Riera, Antoni
• Is Part Of: Angewandte Chemie international edition. Volume 52:Issue 20(2013)
• Page Start: 5355
• Page End: 5359
• Publication Date: 2013-04-10
• Subjects: Chemistry -- Periodicals; 540
• DOI: 10.1002/anie.201300907
• Languages: English
• ISSNs: 1433-7851

Abstract

<abstract abstract-type="graphical" xml:lang="en"> <title> <x xml:space="preserve">Abstract</x> </title> <p> <bold>Against the rules</bold>: The synthesis of the previously unknown β‐substituted regioisomers of the intermolecular Pauson–Khand reaction of terminal alkynes is reported. This regiochemistry was achieved by using the trifluoromethyl group as a removable directing group on the alkyne.<boxed-text content-type="graphic" position="anchor" orientation="portrait"><graphic position="anchor" mimetype="image" xlink:href="ark:/27927/pgg1zsxhh4s" orientation="portrait" xlink:type="simple" xmlns:xlink="http://www.w3.org/1999/xlink" /></boxed-text></p> </abstract>