Copper Salts as Additives in Gold(I)‐Catalyzed Reactions1. Issue 22 (19th April 2013)

• Record Type: Journal Article
• Authors: Guérinot, Amandine; Fang, Weizhen; Sircoglou, Marie; Bour, Christophe; Bezzenine‐Lafollée, Sophie; Gandon, Vincent
• Is Part Of: Angewandte Chemie international edition. Volume 52:Issue 22(2013)
• Page Start: 5848
• Page End: 5852
• Publication Date: 2013-04-19
• Subjects: Chemistry -- Periodicals; 540
• DOI: 10.1002/anie.201300600
• Languages: English
• ISSNs: 1433-7851

Abstract

<abstract abstract-type="graphical" xml:lang="en"> <title> <x xml:space="preserve">Abstract</x> </title> <p> <bold>The right combination</bold>: Cu^I and Cu^II salts can advantageously replace silver additives in Au^I‐catalyzed reactions. On the basis of reactivity studies and NMR experiments, it is believed that anion metathesis between CuY_{<italic>n</italic>} (Y=OTf, BF₄, PF₆, SbF₆) and [R₃PAuCl] takes place to give [R₃PAu]Y. As this process is slow, there is no fast decay of the active species, thus allowing large‐scale reactions, even at high temperatures, with low loadings of the gold complex.<boxed-text content-type="graphic" position="anchor" orientation="portrait"><graphic position="anchor" mimetype="image" xlink:href="ark:/27927/pgg20p4934v" orientation="portrait" xlink:type="simple" xmlns:xlink="http://www.w3.org/1999/xlink" /></boxed-text></p> </abstract>