Palladium‐Catalyzed Migratory Insertion of Isocyanides: An Emerging Platform in Cross‐Coupling Chemistry. Issue 28 (10th June 2013)

• Record Type: Journal Article
• Authors: Vlaar, Tjøstil; Ruijter, Eelco; Maes, Bert U. W.; Orru, Romano V. A.
• Is Part Of: Angewandte Chemie international edition. Volume 52:Issue 28(2013)
• Page Start: 7084
• Page End: 7097
• Publication Date: 2013-06-10
• Subjects: Chemistry -- Periodicals; 540
• DOI: 10.1002/anie.201300942
• Languages: English
• ISSNs: 1433-7851

Abstract

<abstract abstract-type="main" xml:lang="en"> <title>Abstract</title> <p>Isocyanides have been important building blocks in organic synthesis since the discovery of the Ugi reaction and related isocyanide‐based multicomponent reactions. In the past decade isocyanides have found a new application as versatile C₁ building blocks in palladium catalysis. Palladium‐catalyzed reactions involving isocyanide insertion offer a vast potential for the synthesis of nitrogen‐containing fine chemicals. This Minireview discusses all the achievements in this emerging field.</p> </abstract>