Back Cover: A Structured Monodisperse PEG for the Effective Suppression of Protein Aggregation (Angew. Chem. Int. Ed. 9/2013). Issue 9 (1st February 2013)

• Record Type: Journal Article
• Authors: Muraoka, Takahiro; Adachi, Kota; Ui, Mihoko; Kawasaki, Shunichi; Sadhukhan, Nabanita; Obara, Haruki; Tochio, Hidehito; Shirakawa, Masahiro; Kinbara, Kazushi
• Is Part Of: Angewandte Chemie international edition. Volume 52:Issue 9(2013)
• Page Start: 2612
• Page End: 2612
• Publication Date: 2013-02-01
• Subjects: Chemistry -- Periodicals; 540
• DOI: 10.1002/anie.201300347
• Languages: English
• ISSNs: 1433-7851

Abstract

<abstract abstract-type="graphical" xml:lang="en"> <title> <x xml:space="preserve">Abstract</x> </title> <p> <bold>Poly(ethylene glycol)</bold> (PEG) with a discrete triangular structure exhibits hydrophilicity/hydrophobicity switching at a lower temperature than the corresponding linear PEG. In their Communication on <ext-link ext-link-type="doi" xlink:type="simple" xmlns:xlink="http://www.w3.org/1999/xlink">page 2430 ff</ext-link>, T. Muraoka, K. Kinbara, and co‐workers report that such a triangular PEG analogue helps lysozyme preserve the higher order structure at high temperatures and efficiently suppresses its thermal aggregation.<boxed-text content-type="graphic" position="anchor" orientation="portrait"><graphic position="anchor" mimetype="image" xlink:href="ark:/27927/pgg1v49fm26" orientation="portrait" xlink:type="simple" xmlns:xlink="http://www.w3.org/1999/xlink" /></boxed-text></p> </abstract>