Mechanical Carbohydrate Sensors Based on Soft Hydrogel Particles1. Issue 23 (24th April 2013) - Pussak, Daniel
Abstract Elastic sensors: A simple method is presented for the measurement of specific biomolecular interactions with soft colloidal hydrogel particles (SCPs) as sensors. Carbohydrate/lectin interactions (see picture; green: carbohydrate molecules) were studied by optical detection of the mechanical deformation of the particles on a lectin surface. The affinity of various carbohydrate inhibitors could also be readily determined.