A Facile Strategy for Selective Incorporation of Phosphoserine into Histones1. Issue 22 (26th March 2013) - Lee, Sangsik
Abstract Phosphoserine incorporation: A general strategy for producing recombinant histones with site‐specific serine phosphorylation is developed by engineering phosphoseryl‐tRNA synthetase (SepRS) and elongation factor Tu (EF‐Tu; see picture). Serine‐phosphorylated nucleosomes provide direct evidence for crosstalk between phosphorylation and acetylation in histones.