Copper‐Catalyzed Oxidative Cross‐Coupling of Sulfoximines and Alkynes1. Issue 12 (12th February 2013) - Wang, Long
Abstract A 'Cu'te couple: A synthetically useful protocol for the preparation of N‐alkynylated sulfoximines (yne sulfoximines) has been developed. The method involves a mild copper‐catalyzed oxidative cross‐coupling of NH‐sulfoximines and terminal alkynes (see scheme). The corresponding N‐acyl sulfoximines were also obtained selectively after acid‐catalyzed hydrolysis of the yne sulfoximines.