Reactions Templated by Nucleic Acids: More Ways to Translate Oligonucleotide‐Based Instructions into Emerging Function. Issue 27 (12th June 2013)

• Record Type: Journal Article
• Authors: Gorska, Katarzyna; Winssinger, Nicolas
• Is Part Of: Angewandte Chemie international edition. Volume 52:Issue 27(2013)
• Page Start: 6820
• Page End: 6843
• Publication Date: 2013-06-12
• Subjects: Chemistry -- Periodicals; 540
• DOI: 10.1002/anie.201208460
• Languages: English
• ISSNs: 1433-7851

Abstract

<abstract abstract-type="main" xml:lang="en"> <title>Abstract</title> <p>The programmability of oligonucleotide recognition offers an attractive platform to direct the assembly of reactive partners that can engage in chemical reactions. Recently, significant progress has been made in both the breadth of chemical transformations and in the functional output of the reaction. Herein we summarize these recent progresses and illustrate their applications to translate oligonucleotide instructions into functional materials and novel architectures (conductive polymers, nanopatterns, novel oligonucleotide junctions); into fluorescent or bioactive molecule using cellular RNA; to interrogate secondary structures or oligonucelic acids; or a synthetic oligomer.</p> </abstract>