An Air‐Stable Copper Reagent for Nucleophilic Trifluoromethylthiolation of Aryl Halides1. Issue 5 (12th December 2012)

• Record Type: Journal Article
• Authors: Weng, Zhiqiang; He, Weiming; Chen, Chaohuang; Lee, Richmond; Tan, Davin; Lai, Zhiping; Kong, Dedao; Yuan, Yaofeng; Huang, Kuo‐Wei
• Is Part Of: Angewandte Chemie international edition. Volume 52:Issue 5(2013)
• Page Start: 1548
• Page End: 1552
• Publication Date: 2012-12-12
• Subjects: Chemistry -- Periodicals; 540
• DOI: 10.1002/anie.201208432
• Languages: English
• ISSNs: 1433-7851

Abstract

<abstract abstract-type="graphical" xml:lang="en"> <title> <x xml:space="preserve">Abstract</x> </title> <p> <bold>A series of</bold> copper(I) trifluoromethyl thiolate complexes have been synthesized from the reaction of CuF₂ with Me₃SiCF₃ and S₈ (see scheme; Cu red, F green, N blue, S yellow). These air‐stable complexes serve as reagents for the efficient conversion of a wide range of aryl halides into the corresponding aryl trifluoromethyl thioethers in excellent yields.<boxed-text content-type="graphic" position="anchor" orientation="portrait"><graphic position="anchor" mimetype="image" xlink:href="ark:/27927/pgg1p8rs4x5" orientation="portrait" xlink:type="simple" xmlns:xlink="http://www.w3.org/1999/xlink" /></boxed-text></p> </abstract>