An "Against the Rules" Double Bank Shot with Diisobutylaluminum Hydride To Allow Triple Functionalization of α‐Cyclodextrin1. Issue 2 (22nd November 2012)

• Record Type: Journal Article
• Authors: Zaborova, Elena; Guitet, Maxime; Prencipe, Giuseppe; Blériot, Yves; Ménand, Mickaël; Sollogoub, Matthieu
• Is Part Of: Angewandte Chemie international edition. Volume 52:Issue 2(2013)
• Page Start: 639
• Page End: 644
• Publication Date: 2012-11-22
• Subjects: Chemistry -- Periodicals; 540
• DOI: 10.1002/anie.201204974
• Languages: English
• ISSNs: 1433-7851

Abstract

<abstract abstract-type="graphical" xml:lang="en"> <title> <x xml:space="preserve">Abstract</x> </title> <p> <bold>Frustration leads to overreaction</bold>: When diametrically opposed regioselective debenzylation is frustrated, an unexpected double debenzylation reaction affords original tetrafunctionalized cyclodextrins in a controlled and efficient manner. A rationale of the reaction is proposed based on a kinetic study.<boxed-text content-type="graphic" position="anchor" orientation="portrait"><graphic position="anchor" mimetype="image" xlink:href="ark:/27927/pgg1p994q57" orientation="portrait" xlink:type="simple" xmlns:xlink="http://www.w3.org/1999/xlink" /></boxed-text></p> </abstract>