From One‐Photon to Two‐Photon Probes: "Caged" Compounds, Actuators, and Photoswitches. Issue 17 (18th February 2013)

• Record Type: Journal Article
• Authors: Bort, Guillaume; Gallavardin, Thibault; Ogden, David; Dalko, Peter I.
• Is Part Of: Angewandte Chemie international edition. Volume 52:Issue 17(2013)
• Page Start: 4526
• Page End: 4537
• Publication Date: 2013-02-18
• Subjects: Chemistry -- Periodicals; 540
• DOI: 10.1002/anie.201204203
• Languages: English
• ISSNs: 1433-7851

Abstract

<abstract abstract-type="main" xml:lang="en"> <title>Abstract</title> <p>Molecular systems that can be remotely controlled by light are gaining increasing importance in cell biology, physiology, and neurosciences because of the spatial and temporal precision that is achievable with laser microscopy. Two‐photon excitation has significant advantages deep in biological tissues, but raises problems in the design of "smart" probes compatible with cell physiology. This Review discusses the chemical challenges in generating suitable two‐photon probes.</p> </abstract>