Amino Acid Structure Determines the Immune Responses Generated by Peptide–Gold Nanoparticle Hybrids. (16th July 2013)

• Record Type: Journal Article
• Authors: Yang, Hong; Zhou, Yingzhe; Fung, Shan‐Yu; Wu, Licun; Tsai, Kevin; Tan, Rusung; Turvey, Stuart E.; Machuca, Tiago; de Perrot, Marc; Waddell, Thomas K.; Liu, Mingyao
• Is Part Of: Particle and particle systems characterization. Volume 30:Number 12(2013:Dec.)
• Page Start: 1039
• Page End: 1043
• Publication Date: 2013-07-16
• Subjects: Particles -- Periodicals; 620.43
• DOI: 10.1002/ppsc.201300213
• Languages: English
• ISSNs: 0934-0866

Abstract

<abstract abstract-type="graphical" xml:lang="en" id="ppsc201300213-abs-0001"> <title> <x xml:space="preserve">Abstract</x> </title> <p> <bold>By tuning the chemical modalities on gold nanoparticle surface using hexapeptide ligands</bold> the responses of immune cells (dendritic cells) to nanoparticles can be remarkably manipulated from minimum reaction (in the presence of negatively charged peptide ligands) to activation (in the presence of peptide ligands with aromatic rings containing amino acids). <boxed-text content-type="graphic" position="anchor" orientation="portrait"><graphic position="anchor" mimetype="image" xlink:href="ark:/27927/pgg3zn3mz24" orientation="portrait" xlink:type="simple" xmlns:xlink="http://www.w3.org/1999/xlink" /></boxed-text></p> </abstract>