Comparative proteomics lends insight into genotype‐specific pathogenicity. Issue 17 (2nd September 2013)

• Record Type: Journal Article
• Authors: Guarnieri, Michael T.
• Is Part Of: Proteomics. Volume 13:Issue 17(2013:Sep.)
• Page Start: 2544
• Page End: 2545
• Publication Date: 2013-09-02
• Subjects: Proteins -- Separation -- Periodicals; Bioinformatics -- Periodicals; Proteomics -- Periodicals; Genomes -- Periodicals; Molecular genetics -- Periodicals; 572.605
• DOI: 10.1002/pmic.201300322
• Languages: English
• ISSNs: 1615-9853

Abstract

<abstract abstract-type="main"> <title> <x xml:space="preserve">Abstract</x> </title> <p>Comparative proteomic analyses have emerged as a powerful tool for the identification of unique biomarkers and mechanisms of pathogenesis. In this issue of <italic>Proteomics</italic>, Murugaiyan et al. utilize difference gel electrophoresis (DIGE) to examine differential protein expression between nonpathogenic and pathogenic genotypes of <italic>Prototheca zopfii</italic>, a causative agent in bovine enteritis and mastitis. Their findings provide insights into molecular mechanisms of infection and evolutionary adaptation of pathogenic genotypes, demonstrating the power of comparative proteomic analyses.</p> </abstract>