Effect of through‐plane motion on left ventricular rotation: A study using slice‐following harmonic phase imaging. Issue 5 (14th June 2012)

• Record Type: Journal Article
• Authors: Brotman, David; Zhang, Ziheng; Sampath, Smita
• Is Part Of: Magnetic resonance in medicine. Volume 69:Issue 5(2013:May)
• Page Start: 1421
• Page End: 1429
• Publication Date: 2012-06-14
• Subjects: Nuclear magnetic resonance -- Periodicals; Electron paramagnetic resonance -- Periodicals; 616.07548
• DOI: 10.1002/mrm.24373
• Languages: English
• ISSNs: 0740-3194

Abstract

<abstract abstract-type="main" xml:lang="en"> <title>Abstract</title> <p>Noninvasive quantification of regional left ventricular rotation may improve understanding of cardiac function. Current methods used to quantify rotation typically acquire data on a set of prescribed short‐axis slices, neglecting effects due to through‐plane myocardial motion. We combine principles of slice‐following tagged imaging with harmonic phase analysis methods to account for through‐plane motion in regional rotation measurements. We compare rotation and torsion measurements obtained using our method to those obtained from imaging datasets acquired without slice‐following. Our results in normal volunteers demonstrate differences in the general trends of average and regional rotation‐time plots in midbasal slices and the rotation versus circumferential strain loops. We observe substantial errors in measured peak average rotation of the order of 58% for basal slices (due to change in the pattern of the curve), −6.6% for midventricular slices, and −8.5% for apical slices; and an average error in base‐to‐apex torsion of 19% when through‐plane motion is not considered. This study concludes that due to an inherent base‐to‐apex gradient in rotation that exists in the left ventricular, accounting for through‐plane motion is critical to the accuracy of left ventricular rotation quantification. Magn Reson Med, 2013. © 2011 Wiley Periodicals, Inc.</p> </abstract>