Multiple 3D inversion recovery imaging for volume T1 mapping of the heart. Issue 1 (5th April 2012)

• Record Type: Journal Article
• Authors: Coniglio, A.; Di Renzi, P.; Vilches Freixas, G.; Della Longa, G.; Santarelli, A.; Capparella, R.; Nardiello, B.; Loiudice, C.; Bianchi, S.; D'Arienzo, M.; Begnozzi, L.
• Is Part Of: Magnetic resonance in medicine. Volume 69:Issue 1(2013:Jan.)
• Page Start: 163
• Page End: 170
• Publication Date: 2012-04-05
• Subjects: Nuclear magnetic resonance -- Periodicals; Electron paramagnetic resonance -- Periodicals; 616.07548
• DOI: 10.1002/mrm.24248
• Languages: English
• ISSNs: 0740-3194

Abstract

<abstract abstract-type="main" xml:lang="en"> <title>Abstract</title> <p>In this article, a three‐dimensional inversion recovery sequence was optimized with the aim of generating in vivo volume <italic>T</italic>₁ maps of the heart using a 1.5‐T MR system. Acquisitions were performed before and after gadolinium diethylenetriamine penta‐acetic acid (Gd‐DTPA) administration in one patient with hypertrophic cardiomyopathy and in two healthy volunteers. Data were acquired with a multishot fast field echo readout using both ECG and respiratory triggers. A dedicated phantom, composed of four solutions with different <italic>T</italic>₁ values, was positioned on the subjects' thoracic region to perform patient‐specific calibration. Pixel based <italic>T</italic>₁ maps were calculated with a custom Matlab^® code. Phantom measurements showed a good accuracy of the technique and in vivo <italic>T</italic>₁ estimation of liver, skeletal muscle, myocardium, and blood resulted in good agreement with values reported in the literature. Multiple three‐dimensional inversion recovery technique is a feasible and accurate method to perform T₁ volume mapping. Magn Reson Med, 2013. © 2012 Wiley Periodicals, Inc.</p> </abstract>