PH‐Switchable Macroscopic Assembly through Host–Guest Inclusion. Issue 14 (7th June 2013)

• Record Type: Journal Article
• Authors: Yuan, Qi‐Juan; Wang, Yi‐Fu; Li, Jian‐Hu; Li, Bang‐Jing; Zhang, Sheng
• Is Part Of: Macromolecular rapid communications. Volume 34:Issue 14(2013:Jul.)
• Page Start: 1174
• Page End: 1180
• Publication Date: 2013-06-07
• Subjects: Macromolecules -- Periodicals; Polymers -- Periodicals; Chemistry -- Periodicals; 547.705
• DOI: 10.1002/marc.201300289
• Languages: English
• ISSNs: 1022-1336

Abstract

<abstract abstract-type="main" xml:lang="en"> <title>Abstract</title> <p>A novel pH‐switchable macroscopic assembly is reported using alginate‐based hydrogels functionalized with host (α‐cyclodextrin, αCD) and guest (diethylenetriamine, DETA) moieties. Since the interaction of αCD and DETA is pH sensitive, the host hydrogel and guest hydrogel could adhere together when the pH is 11.5 and separate when the pH is 7.0. Furthermore, this pH‐controlled adhesion and dissociation shows a good reversibility. The host and guest polymers have good biocompatibility; therefore, this pH‐sensitive macroscopic assembly shows great potential in biotechnological and biomedical applications.<boxed-text content-type="graphic" position="anchor" orientation="portrait"><graphic position="anchor" mimetype="image" xlink:href="ark:/27927/pgg271jjq58" orientation="portrait" xlink:type="simple" xmlns:xlink="http://www.w3.org/1999/xlink" /></boxed-text></p> </abstract>