Pure Protein Scaffolds from Pickering High Internal Phase Emulsion Template. Issue 2 (12th October 2012)

• Record Type: Journal Article
• Authors: Li, Zifu; Xiao, Manda; Wang, Jianfang; Ngai, To
• Is Part Of: Macromolecular rapid communications. Volume 34:Issue 2(2013:Jan.)
• Page Start: 169
• Page End: 174
• Publication Date: 2012-10-12
• Subjects: Macromolecules -- Periodicals; Polymers -- Periodicals; Chemistry -- Periodicals; 547.705
• DOI: 10.1002/marc.201200553
• Languages: English
• ISSNs: 1022-1336

Abstract

<abstract abstract-type="main" xml:lang="en"> <title>Abstract</title> <p>The formation of hierarchical porous protein scaffolds from oil‐in‐water (o/w) high internal phase emulsions (HIPEs) stabilized by bovine serum albumin (BSA) protein nanoparticles (Pickering HIPE) is reported. The route consists of three principal steps. First, a stable o/w HIPE stabilized by BSA protein nanoparticles is formulated. Next, crosslinking the dispersed protein nanoparticles gives rise to a gel in the continuous water phase to freeze the emulsion's microstructure. Finally, removal of the oil components and water directly leads to a three dimensional, bimodal meso‐macroporous protein scaffold, which is suitable for a wide range of biomedical applications.</p> </abstract>