On the polymorphism of griseofulvin: Identification of two additional polymorphs. Issue 2 (6th November 2012)

• Record Type: Journal Article
• Authors: Mahieu, Aurelien; Willart, Jean‐francois; Dudognon, Emeline; Eddleston, Mark D.; Jones, William; Danède, Florence; Descamps, Marc
• Is Part Of: Journal of pharmaceutical sciences. Volume 102:Issue 2(2013:Feb.)
• Page Start: 462
• Page End: 468
• Publication Date: 2012-11-06
• Subjects: Pharmacy -- Periodicals; 615.1
• DOI: 10.1002/jps.23349
• Languages: English
• ISSNs: 0022-3549

Abstract

<abstract abstract-type="main" xml:lang="en"> <title>Abstract</title> <p>In this paper, we present an investigation of the polymorphism of griseofulvin. In addition to the only reported crystalline form (form I), two new polymorphic forms (II and III) have been identified and characterized by differential scanning calorimetry and powder X‐ray diffraction. Reasons why these two polymorphs were isolated during the present study, but not detected during the numerous previous studies on this drug, are also discussed. © 2012 Wiley Periodicals, Inc. and the American Pharmacists Association J Pharm Sci 102:462–468, 2013</p> </abstract>