A retrospective study of autologous stem cell mobilization to guide an immediate salvage protocol using plerixafor for patients who mobilize stem cells poorly. Issue 5 (11th March 2013)

• Record Type: Journal Article
• Authors: Hay, Annette Elizabeth; Lawrie, Alastair; Robinson, Nicolas; Dong, Bin; Culligan, Dominic J.
• Is Part Of: Journal of clinical apheresis. Volume 28:Issue 5(2014:Oct.)
• Page Start: 378
• Page End: 380
• Publication Date: 2013-03-11
• Subjects: Hemapheresis -- Periodicals; Blood -- Transfusion -- Periodicals; Blood -- Transfusion, Autologous -- Periodicals; Cell separation -- Periodicals; Leukapheresis -- Periodicals; Plasmapheresis -- Periodicals; 615.39
• DOI: 10.1002/jca.21274
• Languages: English
• ISSNs: 0733-2459

Abstract

<abstract abstract-type="main"> <title> <x xml:space="preserve">Abstract</x> </title> <p>The addition of plerixafor to G‐CSF decreases the risk of failed stem cell collection, but at considerable extra cost. Using a logistic regression model based on 354 autologous mobilizations, we have identified a local minimum peripheral blood CD34 count at which the probability of a successful collection is 50%. This seems an appropriate CD34 count at which to add immediate salvage plerixafor. J. Clin. Apheresis 28:378–380, 2013. © 2013 Wiley Periodicals, Inc.</p> </abstract>