Antioxidant Properties and UV Absorbance Pattern of Mycosporine‐Like Amino Acids Analogs Synthesized in an Environmentally Friendly Manner. Issue 6 (3rd May 2013)

• Record Type: Journal Article
• Authors: Andreguetti, Daniel; Stein, Erika M.; Pereira, Claudio M. P.; Pinto, Ernani; Colepicolo, Pio
• Is Part Of: Journal of biochemical and molecular toxicology. Volume 27:Issue 6(2013:Jun.)
• Page Start: 305
• Page End: 312
• Publication Date: 2013-05-03
• Subjects: Biochemistry -- Periodicals; Molecular biology -- Periodicals; Toxicology -- Periodicals; 574
• DOI: 10.1002/jbt.21489
• Languages: English
• ISSNs: 1095-6670

Abstract

<abstract abstract-type="main"> <title>ABSTRACT</title> <p>In current study, we report efficient and clean procedure for preparing mycosporine‐like amino acids (MMAs) analogs and evaluate their ultraviolet absorbance properties and antioxidant activities. The ultraviolet radiation absorbance patterns of the compounds were recorded and then used to define their molar absorptivities. The antioxidant activities were assessed using 1, 1‐diphenyl‐2‐picrylhydrazyl (DPPH) radical scavenging and superoxide radical scavenging assays. Eight of nine compounds showed good activity against superoxide radicals, as only one of the analogs exhibited a measurable IC₅₀ in the DPPH assay. © 2013 Wiley Periodicals, Inc. J BiochemMol Toxicol 27:305‐312, 2013; View this article online at wileyonlinelibrary.com. DOI 10.1002/jbt.21489</p> </abstract>