Development of a dual joystick‐controlled laser trapping and cutting system for optical micromanipulation of chromosomes inside living cells. Issue 2 (20th April 2012)

• Record Type: Journal Article
• Authors: Harsono, Marcellinus S.; Zhu, Qingyuan; Shi, Linda Z.; Duquette, Michelle; Berns, Michael W.
• Is Part Of: Journal of biophotonics. Volume 6:Issue 2(2013:Feb.)
• Page Start: 197
• Page End: 204
• Publication Date: 2012-04-20
• Subjects: Photonics -- Periodicals; Optical materials -- Periodicals; Optics -- Periodicals; Medical instruments and apparatus -- Periodicals; 621.3605
• DOI: 10.1002/jbio.201200019
• Languages: English
• ISSNs: 1864-063X

Abstract

<abstract abstract-type="main" xml:lang="en"> <title>Abstract</title> <p>A multi‐joystick robotic laser microscope system used to control two optical traps (tweezers) and one laser scissors has been developed for subcellular organelle manipulation. The use of joysticks has provided a "user‐friendly" method for both trapping and cutting of organelles such as chromosomes in live cells. This innovative design has enabled the clean severing of chromosome arms using the laser scissors as well as the ability to easily hold and pull the severed arm using the laser tweezers. (© 2013 WILEY‐VCH Verlag GmbH &amp; Co. KGaA, Weinheim)</p> </abstract>