CPAP: Cancer Panel Analysis Pipeline. Issue 10 (13th August 2013)

• Record Type: Journal Article
• Authors: Huang, Po‐Jung; Yeh, Yuan‐Ming; Gan, Ruei‐Chi; Lee, Chi‐Ching; Chen, Ting‐Wen; Lee, Cheng‐Yang; Liu, Hsuan; Chen, Shu‐Jen; Tang, Petrus
• Is Part Of: Human mutation. Volume 34:Issue 10(2013:Oct.)
• Page Start: 1340
• Page End: 1346
• Publication Date: 2013-08-13
• Subjects: Human chromosome abnormalities -- Periodicals; Mutation (Biology) -- Periodicals; 616.04205
• DOI: 10.1002/humu.22386
• Languages: English
• ISSNs: 1059-7794

Abstract

<abstract abstract-type="graphical" xml:lang="en" id="humu22386-abs-0001"> <title> <x xml:space="preserve">Abstract</x> </title> <p>CPAP is a web‐based automatic pipeline to annotate and visualize genomic variants found in cancer panel sequencing. CPAP not only integrates various data sources such as dbSNP, the 1000 Genomes Project, and COSMIC, but also provides the prediction of the functional impact of variants as generated by popular prediction tools (e.g., PolyPhen, SIFT, and MutationTaster). The generated results can be viewed either in the Circos view with pop‐up annotations or in the Table view, where results are filterable. <boxed-text content-type="graphic" position="anchor" orientation="portrait"><graphic position="anchor" mimetype="image" xlink:href="ark:/27927/pgg3hnbnndp" orientation="portrait" xlink:type="simple" xmlns:xlink="http://www.w3.org/1999/xlink" /></boxed-text></p> </abstract>