An Overview of Synergistic Data Tools for Biological Scrutiny. Issue 3 (15th April 2013)

• Record Type: Journal Article
• Authors: Olender, Tsviya; Safran, Marilyn; Edgar, Ron; Stelzer, Gil; Nativ, Noam; Rosen, Naomi; Shtrichman, Ronit; Mazor, Yaron; West, Michael D.; Keydar, Ifat; Rappaport, Noa; Belinky, Frida; Warshawsky, David; Lancet, Doron
• Is Part Of: Israel journal of chemistry. Volume 53:Issue 3/4(2013)
• Page Start: 185
• Page End: 198
• Publication Date: 2013-04-15
• Subjects: Chemistry -- Periodicals; 540.5
• DOI: 10.1002/ijch.201200094
• Languages: English
• ISSNs: 0021-2148

Abstract

<abstract abstract-type="main" xml:lang="en"> <title>Abstract</title> <p>A network of biological databases is reviewed, supplying a framework for studies of human genes and the association of their genomic variations with human phenotypes. The network is composed of GeneCards, the human gene compendium, which provides comprehensive information on all known and predicted human genes, along with its suite members GeneDecks and GeneLoc. Two databases are shown that address genes and variations focusing on olfactory reception (HORDE) and transduction (GOSdb). In the realm of disease scrutiny, we portray MalaCards, a novel comprehensive database of human diseases and their annotations. Also shown is GeneKid, a tool aimed at generating novel kidney disease biomarkers using systems biology, as well as Xome, a database for whole‐exome next‐generation DNA sequences for human diseases in the Israeli population. Finally, we show LifeMap Discovery, a database of embryonic development, stem cell research and regenerative medicine, which links to both GeneCards and MalaCards.</p> </abstract>