A Genome‐Wide Assessment of Variability in Human Serum Metabolism. Issue 3 (18th February 2013)

• Record Type: Journal Article
• Authors: Hong, Mun‐Gwan; Karlsson, Robert; Magnusson, Patrik K. E.; Lewis, Matthew R.; Isaacs, William; Zheng, Lilly S.; Xu, Jianfeng; Grönberg, Henrik; Ingelsson, Erik; Pawitan, Yudi; Broeckling, Corey; Prenni, Jessica E.; Wiklund, Fredrik; Prince, Jonathan A.
• Is Part Of: Human mutation. Volume 34:Issue 3(2013:Mar.)
• Page Start: 515
• Page End: 524
• Publication Date: 2013-02-18
• Subjects: Human chromosome abnormalities -- Periodicals; Mutation (Biology) -- Periodicals; 616.04205
• DOI: 10.1002/humu.22267
• Languages: English
• ISSNs: 1059-7794

Abstract

<abstract abstract-type="graphical" xml:lang="en" id="humu22267-abs-0001"> <title> <x xml:space="preserve">Abstract</x> </title> <p>A genome‐wide association study of metabolic quantitative traits (mQTLs) was conducted in Swedish men. A global non‐targeted metabolite profiling approach was used resulting in the identification of both novel mQTLs and replication of previously described associations. Analyses involving biological pathways and a search for enrichment of mQTLs across the genome highlighted additional novel loci. <boxed-text content-type="graphic" position="anchor" orientation="portrait"><graphic position="anchor" mimetype="image" xlink:href="ark:/27927/pgg1tt8dhxd" orientation="portrait" xlink:type="simple" xmlns:xlink="http://www.w3.org/1999/xlink" /></boxed-text></p> </abstract>