A Novel Xanthone from Garcinia oligantha. Issue 3 (13th March 2013)

• Record Type: Journal Article
• Authors: Gao, Xue‐Mei; Cui, Ming‐Zhu; Yu, Ting; Hu, Qiu‐Fen; Pu, Jian‐Xin; Du, Xue; Liu, Tian‐Cheng; Qian Luo, Kathy
• Is Part Of: Helvetica chimica acta. Volume 96:Issue 3(2013:Mar.)
• Page Start: 494
• Page End: 498
• Publication Date: 2013-03-13
• Subjects: Chemistry -- Periodicals; Chemistry, Analytical -- periodicals; Chimie -- Périodiques; 540
• DOI: 10.1002/hlca.201200245
• Languages: English
• ISSNs: 0018-019X

Abstract

<abstract abstract-type="main" xml:lang="en"> <title>Abstract</title> <p>One novel xanthone, oliganthone A (<bold>1</bold>), was isolated from the stems of the plant <italic>Garcinia oligantha.</italic> It features the O‐bearing C(3)‐atom and absence of C(4) compared with the structures of related known xanthones, which have never been reported before. The structure of this compound was elucidated by spectroscopic analysis. Compound <bold>1</bold> showed strong HeLa cell growth‐inhibiting effects with <italic>IC</italic>₅₀ values below 10 μ<sc>M</sc>.</p> </abstract>