The role of elective neck dissection in patients undergoing salvage laryngectomy. Issue 10 (28th September 2012)

• Record Type: Journal Article
• Authors: Amit, Moran; Hilly, Ohad; Leider–Trejo, Leonor; Popovtzer, Aharon; Gutfeld, Orit; Shvero, Jacob; Fliss, Dan M.; Cohen, Jacob T.; Bachar, Gideon; Gil, Ziv
• Is Part Of: Head & neck. Volume 35:Issue 10(2013:Oct.)
• Page Start: 1392
• Page End: 1396
• Publication Date: 2012-09-28
• Subjects: Head -- Diseases -- Periodicals; Neck -- Diseases -- Periodicals; Head -- Periodicals; Neck -- Periodicals; Face -- Periodicals; 617.51059
• DOI: 10.1002/hed.23145
• Languages: English
• ISSNs: 1043-3074

Abstract

<abstract abstract-type="main"> <title> <x xml:space="preserve">Abstract</x> </title> <sec id="hed23145-sec-0001" sec-type="section"> <title>Background</title> <p>We investigated the risk of neck metastases in patients undergoing salvage total laryngectomy in association with previous radiotherapy.</p> </sec> <sec id="hed23145-sec-0002" sec-type="section"> <title>Methods</title> <p>The medical records of 42 patients (51 neck specimens) with clinical N0 classification who underwent salvage total laryngectomy in 2 cancer centers were reviewed. Fourteen patients had previous radiotherapy to the central neck and 28 to the central and lateral neck.</p> </sec> <sec id="hed23145-sec-0003" sec-type="section"> <title>Results</title> <p>Staging before salvage total laryngectomy was similar in both groups. The risk of neck metastases in the central and central/lateral radiation groups was 12% and 18%, respectively (<italic>p</italic> = .69). Subgroup analysis revealed that 4 of 8 patients initially presenting with clinically N+ had neck metastases before surgery, versus 2 of 26 for those with clinically N0 (<italic>p</italic> = .015; relative risk [RR] = 4.67). The risk or metastases in the contralateral neck was 0 of 9.</p> </sec> <sec id="hed23145-sec-0004" sec-type="section"> <title>Conclusion</title> <p>The risk of neck metastases in patients who undergo either central or central/lateral neck radiotherapy is similar. Elective neck dissection seems appropriate in patients undergoing SLR. © 2012 Wiley Periodicals, Inc. <italic>Head Neck</italic> 35: 1392–1396, 2013</p> </sec> </abstract>