Primary intestinal‐like adenocarcinoma of major salivary glands: 2 instances of previously undocumented phenotype. Issue 8 (29th October 2012)

• Record Type: Journal Article
• Authors: Gillenwater, Ann M.; Frank, Steven J.; Fatani, Hanadi; El–Naggar, Adel K.; Irish, Jonathan
• Is Part Of: Head & neck. Volume 35:Issue 8(2013:Aug.)
• Page Start: E234
• Page End: E236
• Publication Date: 2012-10-29
• Subjects: Head -- Diseases -- Periodicals; Neck -- Diseases -- Periodicals; Head -- Periodicals; Neck -- Periodicals; Face -- Periodicals; 617.51059
• DOI: 10.1002/hed.23059
• Languages: English
• ISSNs: 1043-3074

Abstract

<abstract abstract-type="main" xml:lang="en"> <title>Abstract</title> <sec id="abs1-1" sec-type="section"> <title>Background</title> <p>Primary intestinal‐like adenocarcinoma of the major salivary glands has not previously been reported.</p> </sec> <sec id="abs1-2" sec-type="section"> <title>Methods</title> <p>The clinical and radiological findings of 2 patients with primary submandibular and sublingual tumors are presented. Histopathologic and immunohistochemical examinations of tumor sections were performed. Metastatic workup for distant occult primary was carried out.</p> </sec> <sec id="abs1-3" sec-type="section"> <title>Results</title> <p>The light‐optic and the immunomarkers revealed intestinal‐like adenocarcinoma consistent with upper respiratory tract origin. Metastatic workup of both patients was negative for primary gastro‐intestinal primary.</p> </sec> <sec id="abs1-4" sec-type="section"> <title>Conclusion</title> <p>Primary intestinal‐like adenocarcinoma can develop in major salivary glands and should be considered in the differential diagnosis. © 2012 Wiley Periodicals, Inc. Head Neck, 2012</p> </sec> </abstract>